Nonlinear Biomedical Physics

EPJ E - Electric charge disorder: A key to biological order?

Strong attraction that arises between biological objects with random patches of electric charge on an otherwise neutral surface may partly explain pattern recognition in biology.

Theoretical physicist Ali Naji from the IPM in Tehran and the University of Cambridge, UK, and his colleagues have shown how small random patches of disordered, frozen electric charges can make a difference when they are scattered on surfaces that are overall neutral. These charges induce a twisting force that is strong enough to be felt as far as nanometers or even micrometers away. These results, just published in EPJE, could help to understand phenomena that occurr on surfaces such as those of large biological molecules.

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EPJ E - Study on swirls to optimise contacts between fluids

Model gives clues on how to optimize homogeneous feeding of cells in suspension from a liquid nutriments supply in a bioreactor.

Physicists who have studied the mixing between two incompatible fluids have found that it is possible to control the undercurrents of one circulating fluid to optimise its exposure to the other. This work, which has just been published in EPJE, was performed by Jorge Peixinho from CNRS at Le Havre University, France, and his colleagues from the Benjamin Levich Institute, City University of New York, USA.

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Jean Francois Joanny awarded the 2012 Gentner-Kastler prize

The German Physical Society (DPG) and the French Physical Society (SFP) will present the 2012 Gentner-Kastler award to Professor Jean Francois Joanny of the Institut Curie, France. The former Editor in Chief and current External Advisor of EPJ E is nominated for his extraordinary contributions to the theory of soft matter, particularly for his work in polymer physics and biological physics. The prize will be presented March 29, 2012, during the Meeting of the German Physical Society in Berlin.

The Gentner-Kastler prize is awarded jointly by the German Physical Society for works in physics done alternatively in Germany or France.

EPJ E - Cosmology in a petri dish

To understand long-range interactions between particles at the micrometric scale, researchers utilize methods which are used to study the formation of our universe.

Scientists have found that micron-size particles which are trapped at fluid interfaces exhibit a collective dynamic that is subject to seemingly unrelated governing laws. These laws show a smooth transitioning from long-ranged cosmological-style gravitational attraction down to short-range attractive and repulsive forces. The study by Johannes Bleibel from the Max Planck Institute for Intelligent Systems in Stuttgart, Germany, and his colleagues has just been published in the journal EPJE.

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EPJ E - How to build doughnuts with Lego blocks

Controlling forces between oppositely charged polymers opens a new route towards creating vectors for gene therapy

Scientists have uncovered how nature minimises energy costs in rings of liquids with an internal nanostructure made of two chemically discordant polymers joined with strong bonds, or di-blocks, deposited on a silicon surface, in an article published in EPJE.

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EPJ E - The art of stabilising entangled spaghetti-like materials

Controlling forces between oppositely charged polymers opens a new route towards creating vectors for gene therapy

Gene therapy can only be effective if delivered by a stable complex molecule. Now, scientists have determined the conditions that would stabilise complex molecular structures that are subject to inherent attractions and repulsions triggered by electric charges at the surfaces of the molecules, in a study published in EPJE, by Valentina Mengarelli and her colleagues from the Solid State Physics Laboratory at the Paris-Sud University in Orsay, France, in collaboration with Paris 7 and Evry Universities scientists.

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EPJ E - How biological capsules respond under stress

Innovative high-precision measuring tool to assess the bending elasticity of liposomes

Cosmetics and pharmaceutical drug delivery systems could be improved thanks to a new method developed to precisely measure the capability of capsule-like biological membranes to change shape under external stress. This work is outlined in a study published in EPJE by Philippe Méléard and Tanja Pott from the Rennes-based Institute of Chemical Sciences at the European University of Brittany and their colleagues from the Center for Biomembrane Physics at the University of Southern Denmark in Odense.

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EPJ E - How do protein binding sites stay dry in water?

In a report that has just been published in EPJE, researchers from the National University of the South in Bahía Blanca, Argentina studied the condition for model cavity and tunnel structures resembling the binding sites of proteins to stay dry without losing their ability to react, a prerequisite for proteins to establish stable interactions with other proteins in water.

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EPJ E - What makes tires grip the road on a rainy day?

Scientists examine the flow of liquid at the contact between randomly rough surfaces

A team of scientists from Italy and Germany has recently developed a model to predict the friction occurring when a rough surface in wet conditions (such as a road on a rainy day) is in sliding contact with a rubber material (such as a car tire tread block) in an article that has just been published in EPJE.

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EPJ E - New complex offers potentially safer alternative for gene therapy delivery

Spontaneous ordering of DNA fragments in a special matrix holds the key to creating non-toxic gene therapy delivery vectors, according to a study recently published in the European Physical Journal E.

Scientists from the CNRS Paul Pascal Research Centre, an institute of the University of Bordeaux, France, and colleagues from the Institute of Physics at the University of Sao Paolo, have created a complex system designed to hold DNA fragments in solution between the hydrophilic layers of a matrix of fatty substances (also known as lipids) combined with a surfactant (used to soften the layers’ rigidity). One possible application that has yet to be tested is gene therapy.

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Section Editors-in-Chief
W. Klonowski, A. Stefanovska, J. Tuszynski, M.-T. Huett and V. Jirsa
ISSN (Electronic Edition): 2195-0008

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